Critical Environment Technologies
    Traditional Refrigerants

    R-448A

    R32/R125/R13…

    R-448A (Solstice N40) is an HFO/HFC refrigerant blend designed as a lower-GWP replacement for R-404A and R-507A in commercial refrigeration applications. With a GWP of 1,387—approximately 65% lower than R-404A—R-448A offers significant environmental improvement while maintaining A1 safety classification. The blend contains HFO-1234yf and HFO-1234ze(E) along with R-32, R-125, and R-134a, providing the low-GWP benefits of HFO technology. R-448A is suitable for medium and low-temperature refrigeration in supermarkets, convenience stores, and cold storage. The blend is compatible with POE lubricants and can be used in new equipment or as a retrofit with appropriate system modifications.

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    Key Information

    Essential safety and exposure information for R-448A

    Health Effects

    Low acute toxicity. Non-flammable classification (A1). May cause cardiac sensitization at high concentrations.

    Common Sources

    • Supermarket refrigeration
    • commercial cold storage
    • food retail

    Exposure Limits

    WEEL
    1,000 ppm (8-hr TWA)
    No OSHA/NIOSH limit
    No OSHA/NIOSH limit
    HFO blend
    HFO blend

    Regulatory Status

    EPA Classification
    HFC/HFO blend (non-ODS)
    ASHRAE Safety Group
    A1 (low toxicity, non-flammable)
    GWP (AR5)
    1,387
    ODP
    0
    AIM Act
    Lower priority due to reduced GWP
    EU F-gas
    Approved for refrigeration applications

    Detection Requirements

    Sensor Technology
    Infrared (NDIR)
    Detection Range
    0-1,000 ppm typical
    Response Time
    <30 seconds (T90)
    Calibration Frequency
    Annual recommended
    HFO Content
    Contains HFO-1234yf and HFO-1234ze(E)