R-422A
R125/R134a/I…R-422A is an HFC refrigerant blend developed as a retrofit replacement for R-22 in medium and low-temperature refrigeration applications. The blend composition is optimized to match R-22 capacity and efficiency in refrigeration systems with minimal modifications. R-422A operates at similar pressures to R-22 and is compatible with conventional mineral oil in many applications. With a GWP of approximately 3,100, R-422A is subject to significant regulatory pressure under current phase-down requirements. The refrigerant has been used in commercial refrigeration, supermarket systems, and industrial cooling where direct R-22 replacement was needed.
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Key Information
Essential safety and exposure information for R-422A
Health Effects
Low acute toxicity. Contains small percentage of flammable component. Avoid inhalation of high concentrations.
Common Sources
- Commercial refrigeration
- supermarkets
- food processing
Exposure Limits
- WEEL
- 1,000 ppm (8-hr TWA)
- No OSHA/NIOSH limit
- No OSHA/NIOSH limit
- Blend with R125/R134a
- Blend with R125/R134a
Regulatory Status
- EPA Classification
- HFC blend (non-ODS)
- ASHRAE Safety Group
- A1 (low toxicity, non-flammable)
- GWP (AR5)
- ~3,100
- ODP
- 0
- AIM Act
- Subject to phase-down due to high GWP
- Use Case
- R-22 retrofit in refrigeration systems
Detection Requirements
- Sensor Technology
- Infrared (NDIR)
- Detection Range
- 0-1,000 ppm typical
- Response Time
- <30 seconds (T90)
- Calibration Frequency
- Annual recommended
- Pressure
- Similar to R-22 operating pressures
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