R-422A
R125/R134a/I…R-422A is an HFC refrigerant blend developed as a retrofit replacement for R-22 in medium and low-temperature refrigeration applications. The blend composition is optimized to match R-22 capacity and efficiency in refrigeration systems with minimal modifications. R-422A operates at similar pressures to R-22 and is compatible with conventional mineral oil in many applications. With a GWP of approximately 3,100, R-422A is subject to significant regulatory pressure under current phase-down requirements. The refrigerant has been used in commercial refrigeration, supermarket systems, and industrial cooling where direct R-22 replacement was needed.
Need R-422A Detection?
Get expert guidance on the right detection solution for your application.
Key Information
Essential safety and exposure information for R-422A
Health Effects
Low acute toxicity. Contains small percentage of flammable component. Avoid inhalation of high concentrations.
Common Sources
- Commercial refrigeration
- supermarkets
- food processing
Exposure Limits
- WEEL
- 1,000 ppm (8-hr TWA)
- No OSHA/NIOSH limit
- No OSHA/NIOSH limit
- Blend with R125/R134a
- Blend with R125/R134a
Regulatory Status
- EPA Classification
- HFC blend (non-ODS)
- ASHRAE Safety Group
- A1 (low toxicity, non-flammable)
- GWP (AR5)
- ~3,100
- ODP
- 0
- AIM Act
- Subject to phase-down due to high GWP
- Use Case
- R-22 retrofit in refrigeration systems
Detection Requirements
- Sensor Technology
- Infrared (NDIR)
- Detection Range
- 0-1,000 ppm typical
- Response Time
- <30 seconds (T90)
- Calibration Frequency
- Annual recommended
- Pressure
- Similar to R-22 operating pressures
Detection Solutions
Sensors and detectors for R-422A monitoring

cGas Detector VRF IR Refrigerant Transmitter
An aesthetic, non-dispersive infrared refrigerant gas detector for acute leak detection in modern energy-efficient buildings utilizing Variable Refrigerant Flow (VRF) HVAC systems.

cGas-SC Self-Contained Controller
A self contained controller with up to 3 gas channels, Plug & Play Smart Sensor Technology and configurable logic control and priority settings. Offers superior user customization and reliable gas detection performance for monitoring many gases.

cGas Detector IR Refrigerant Transmitter
Non-dispersive infrared refrigerant gas detector with accurate, low level leak detection, available with analog output or BACnet® or Modbus® output and Plug & Play Smart Sensor Technology.

FCS Multi Channel System Controllers
High performance controller with logic and priority settings for monitoring toxic, combustible and refrigerant gases with versatile control functionality. Available with Modbus® or BACnet® communication with BAS, supports 4-20 mA and Modbus® driven VFDs.