Critical Environment Technologies
    Traditional Refrigerants

    R-143a

    C₂H₃F₃

    R-143a (1,1,1-trifluoroethane, HFC-143a) is a hydrofluorocarbon primarily used as a component in refrigerant blends rather than as a standalone refrigerant. R-143a is a key component of R-404A (52%), R-507A (50%), and R-452A (30%), contributing to the thermodynamic properties of these low-temperature refrigerant blends. With a high GWP of 4,470, R-143a-containing blends are subject to stringent phase-down regulations. R-143a is classified as A2L due to mild flammability, though when blended with non-flammable components, the resulting mixtures are typically non-flammable. Understanding R-143a properties is important for technicians working with common commercial refrigeration blends and for leak detection system calibration.

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    Key Information

    Essential safety and exposure information for R-143a

    Health Effects

    May cause cardiac sensitization at high concentrations. Vapor can displace oxygen and cause asphyxiation in confined spaces.

    Common Sources

    • Component in R-404A
    • R-507A blends
    • commercial refrigeration systems

    Exposure Limits

    WEEL
    1,000 ppm (8-hr TWA)
    No OSHA/NIOSH limit
    No OSHA/NIOSH limit
    Simple asphyxiant hazard
    Simple asphyxiant hazard

    Regulatory Status

    EPA Classification
    HFC (non-ODS)
    ASHRAE Safety Group
    A2L (low toxicity, mildly flammable)
    GWP (AR5)
    4,470
    ODP
    0
    Primary Use
    Component in R-404A, R-507A, R-452A blends
    AIM Act
    Blends containing R-143a subject to phase-down

    Detection Requirements

    Sensor Technology
    Infrared (NDIR)
    Detection Range
    0-1,000 ppm as component, 0-5,000 ppm in blends
    Response Time
    <30 seconds (T90)
    Calibration Frequency
    Annual recommended
    Blend Detection
    Usually detected as part of R-404A, R-507A, or R-452A