R-407C
R32/R125/R134aR-407C is a zeotropic HFC refrigerant blend (R-32/R-125/R-134a at 23/25/52%) designed as a direct retrofit replacement for R-22 in air conditioning and heat pump systems. With operating pressures and capacity similar to R-22, R-407C enables conversion of existing equipment with minimal modifications—typically only requiring oil change to POE and adjustment of expansion devices. The GWP of 1,774 positions R-407C between R-22 and R-410A environmentally. Temperature glide of approximately 7°C requires consideration for heat exchangers but is manageable in most AC applications. R-407C remains widely used for R-22 retrofit projects, particularly where equipment modification costs must be minimized.
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Key Information
Essential safety and exposure information for R-407C
Health Effects
Low toxicity classification. May cause cardiac sensitization at high concentrations. Vapor can displace oxygen.
Common Sources
- Residential air conditioning
- commercial HVAC
- chiller retrofits
Exposure Limits
- WEEL
- 1,000 ppm (8-hr TWA)
- No OSHA/NIOSH limit
- No OSHA/NIOSH limit
- Blend of R32/R125/R134a
- Blend of R32/R125/R134a
Regulatory Status
- EPA Classification
- HFC blend (non-ODS)
- ASHRAE Safety Group
- A1 (low toxicity, non-flammable)
- GWP (AR5)
- 1,774
- ODP
- 0
- Temperature Glide
- Approximately 7°C
- AIM Act
- Subject to sector-based phase-down
Detection Requirements
- Sensor Technology
- Infrared (NDIR)
- Detection Range
- 0-1,000 ppm typical
- Response Time
- <30 seconds (T90)
- Calibration Frequency
- Annual recommended
- Temperature Glide
- 7°C - charge as liquid only
Related Applications
Industries and environments where R-407C detection is critical
Hotels
Continuous monitoring of refrigerant gases in hotel rooms are used to keep the indoor environment comfortable.
Data Centers
Refrigerant leaks from cooling infrastructure can create asphyxiation risks, while hydrogen off‑gassing from battery systems can form an explosive hazard.
Detection Solutions
Sensors and detectors for R-407C monitoring

cGas Detector VRF IR Refrigerant Transmitter
An aesthetic, non-dispersive infrared refrigerant gas detector for acute leak detection in modern energy-efficient buildings utilizing Variable Refrigerant Flow (VRF) HVAC systems.

cGas-SC Self-Contained Controller
A self contained controller with up to 3 gas channels, Plug & Play Smart Sensor Technology and configurable logic control and priority settings. Offers superior user customization and reliable gas detection performance for monitoring many gases.

cGas Detector IR Refrigerant Transmitter
Non-dispersive infrared refrigerant gas detector with accurate, low level leak detection, available with analog output or BACnet® or Modbus® output and Plug & Play Smart Sensor Technology.

FCS Multi Channel System Controllers
High performance controller with logic and priority settings for monitoring toxic, combustible and refrigerant gases with versatile control functionality. Available with Modbus® or BACnet® communication with BAS, supports 4-20 mA and Modbus® driven VFDs.